| Early detection of right ventricular functional abnormalities in patients with complex right premature ventricular contractions. | |
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MedLine Citation:
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PMID: 18769308 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Right ventricular (RV) premature contractions, although generally benign, may represent the first manifestation of arrhythmogenic RV cardiomyopathy. The diagnostic and prognostic value of RV functional abnormalities evidenced by equilibrium radionuclide angiocardiography (ERNA) with multiharmonic Fourier analysis has been validated in patients with severe RV arrhythmias suspected of being affected by arrhythmogenic RV cardiomyopathy. The aim of this study was to assess the prevalence of the same RV functional abnormalities in patients with frequent left bundle branch block pattern premature ventricular contractions (PVCs), without known heart disease, using ERNA as a screening tool. METHODS: The study included 377 consecutive patients (mean age: 40+/-15 years, males: 58%) presenting with complex PVCs. Cine mode and multiharmonic analysis were used to define global enlargement and areas of dyskinesia of both ventricles. Studies were classified as: normal, right and/or left ventricular abnormalities either localized or diffuse. RESULTS: ERNA was normal in 302 patients (80%) and evidenced RV functional abnormalities in 75 patients (20%). Patients with RV outflow tract PVCs (n=276) were affected to the same extent as patients with right or left axis PVCs. CONCLUSION: In a specific population with complex left bundle branch block pattern PVCs, RV functional abnormalities were detected by ERNA in 20% of patients. Consequently, ERNA may serve as a screening tool by selecting patients who may require a specific management. |
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Authors:
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Francois Rouzet; Laure Sarda-Mantel; Rachida Lebtahi; Sylvie Dinanian; Robert Frank; Doumit Daou; Antoine Leenhardt; Michel S Slama; Dominique Le Guludec |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 29 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-09-04 Completed Date: 2009-01-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
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Languages: eng Pagination: 901-6 Citation Subset: IM |
Affiliation:
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AP-HP, Bichat Hospital bINSERM, Lariboisière Hospital, Paris, France. francois.rouzet@bch.aphp.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angiocardiography Bundle-Branch Block / physiopathology, radiography, radionuclide imaging Female Fourier Analysis Humans Male Middle Aged Radiopharmaceuticals / diagnostic use Tachycardia, Ventricular / radionuclide imaging* Technetium / diagnostic use Ventricular Dysfunction, Right / radiography*, radionuclide imaging Ventricular Premature Complexes / physiopathology, radiography*, radionuclide imaging Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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