| Early detection of recurrence after endoscopic treatment for early gastric cancer. | |
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MedLine Citation:
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PMID: 19593687 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: Although there have been many reports regarding clinical outcomes of endoscopic treatment for early gastric cancer (EGC), little is known about detection of recurrence after endoscopic submucosal dissection (ESD). This study aims to clarify the clinical value of serological marker or imaging tools, including conventional CT and PET-CT scans, in detecting recurrent gastric cancer after ESD in Korea. MATERIAL AND METHODS: From July 2004 to March 2008, 212 patients who had received ESD for EGC were enrolled in the study. For preoperative staging, conventional CT and PET-CT scans were performed in 141 patients, and for detection of recurrence of cancer, conventional CT, PET-CT scans and tumour marker; CEA, CA19-9, AFP were checked in 165 patients. RESULTS: The local recurrence rate was 4.7% (10/212) during the study period. At 9 months after endoscopic treatment, 3 cases recurred. Four showed recurrence at 12 months, 2 at 18 months and 1 at 24 months. The positive rate was 7.1% (10/141) in conventional CT and 0% (0/24) in PET-CT scans for preoperative staging. Conventional CT and PET-CT scans could not detect local recurrence of cancer during the follow-up period. Tumour markers did not show any significant correlation with recurrence of cancer. CONCLUSIONS: The study suggests that conventional CT, PET-CT scans and tumour marker have no role in the primary surveillance of early gastric cancer and/or in detecting recurrence after endoscopic treatment. For early diagnosis of recurrence after endoscopic treatment, a biopsy specimen from the endoscopic examination has to be obtained at regular intervals. |
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Authors:
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You Jung Sohn; Jin Seok Jang; Seok Reyol Choi; Hyuk-Chan Kwon; Ghap Joong Jung; Min Chan Kim; Jin Sook Jeong |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Scandinavian journal of gastroenterology Volume: 44 ISSN: 1502-7708 ISO Abbreviation: Scand. J. Gastroenterol. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-11-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0060105 Medline TA: Scand J Gastroenterol Country: England |
Other Details:
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Languages: eng Pagination: 1109-14 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Dong-A Medical Center, University of College of Medicine, Busan, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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