Document Detail


Early detection of median nerve syndrome at the carpal tunnel with high-resolution 18 MHz ultrasonography in systemic sclerosis patients.
MedLine Citation:
PMID:  21050540     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To investigate carpal tunnel syndrome (CTS) with ultrasound (US) in asymptomatic SSc patients and to seek out the relationship between CTS and SSc clinical variables
METHODS: In 64 SSc patients (55 women and 9 men, mean age 57±14 years) and in 30 healthy controls, area (MNA), transverse (MNT) and anteroposterior (MNAP) diameters of MN at carpal tunnel were studied with US (My Lab 25 XVG US Esaote 18 MHz). MN flattening ratio (MNFR) was calculated. Duration of disease, subset (limited, diffuse), phase of skin involvement (oedematous, atrophic, fibrotic), modified Rodnan skin score (mRSS) and friction tendon rub were also recorded.
RESULTS: MNA (p<0.001), MNT (p<0.005) and MNFR (p<0.005) were significantly higher in the SSc patients than in controls, while no difference in MNAP was found. There was no correlation between median nerve (MN) and SSc clinical features (only lower MNAP correlated inversely with longer disease duration; Spearman coefficient -0.2).
CONCLUSIONS: MN involvement is frequently present in all phases of asymptomatic SSc patients, independently to clinical variables.
Authors:
F Bandinelli; O Kaloudi; A Candelieri; M L Conforti; R Casale; S Cammarata; G Grassiri; I Miniati; D Melchiorre; M Matucci-Cerinic
Publication Detail:
Type:  Journal Article     Date:  2010-11-03
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  28     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-11-05     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  S15-8     Citation Subset:  IM    
Affiliation:
Department of Medicine, DENOThe Centre, Division of Rheumatology AOUC, University of Florence, Florence, Italy. bandin@hotmail.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Asymptomatic Diseases
Carpal Tunnel Syndrome / etiology,  physiopathology,  ultrasonography*
Early Diagnosis
Female
Health Status
Humans
Male
Median Nerve / physiopathology,  ultrasonography
Middle Aged
Scleroderma, Diffuse / complications,  physiopathology,  ultrasonography*
Scleroderma, Limited / complications,  physiopathology,  ultrasonography*
Severity of Illness Index
Skin / pathology
Ultrasonography / methods*
Young Adult

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