Document Detail

Early detection of colorectal cancer using faecal occult blood tests.
MedLine Citation:
PMID:  6463799     Owner:  NLM     Status:  MEDLINE    
Five thousand and twelve asymptomatic patients over the age of 40 years who were on a normal diet were asked by their general practitioners to perform a Hemoccult (Röhn Pharma (Noristan] faecal occult blood test over 3 days. Of the 3 422 patients (68%) who completed the test, 99 (3%) had a positive result. The patients with a positive result then again performed the Hemoccult test, this time over 6 days on a restricted diet. Thirty-two of these patients had a positive result on the second test. Only the 32 patients who had a positive result for the second test were fully investigated (including double-contrast barium enema and colonoscopy); 27 patients (84%) were found to have neoplastic disease. Twelve had invasive carcinoma (9 Dukes' A, 2 Dukes' B and 1 Dukes' C), 6 of these also having 10 adenomas, while the other 15 had 27 adenomas which were identified and removed at colonoscopy. Barium enema missed 3 carcinomas (all Dukes' A) and identified only 16 (43%) of the 37 adenomas. Those patients found to have a negative result for the second Hemoccult test are being followed up.
M S Elliot; J H Levenstein; J P Wright; R E Kottler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  66     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-09-11     Completed Date:  1984-09-11     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  219-21     Citation Subset:  IM    
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MeSH Terms
Adenocarcinoma / diagnosis
Adenoma / diagnosis
Colonic Neoplasms / diagnosis*
Occult Blood*
Reagent Kits, Diagnostic
Rectal Neoplasms / diagnosis*
Reg. No./Substance:
0/Reagent Kits, Diagnostic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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