Document Detail


Early detection of colorectal cancer using faecal occult blood tests.
MedLine Citation:
PMID:  6463799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Five thousand and twelve asymptomatic patients over the age of 40 years who were on a normal diet were asked by their general practitioners to perform a Hemoccult (Röhn Pharma (Noristan] faecal occult blood test over 3 days. Of the 3 422 patients (68%) who completed the test, 99 (3%) had a positive result. The patients with a positive result then again performed the Hemoccult test, this time over 6 days on a restricted diet. Thirty-two of these patients had a positive result on the second test. Only the 32 patients who had a positive result for the second test were fully investigated (including double-contrast barium enema and colonoscopy); 27 patients (84%) were found to have neoplastic disease. Twelve had invasive carcinoma (9 Dukes' A, 2 Dukes' B and 1 Dukes' C), 6 of these also having 10 adenomas, while the other 15 had 27 adenomas which were identified and removed at colonoscopy. Barium enema missed 3 carcinomas (all Dukes' A) and identified only 16 (43%) of the 37 adenomas. Those patients found to have a negative result for the second Hemoccult test are being followed up.
Authors:
M S Elliot; J H Levenstein; J P Wright; R E Kottler
Related Documents :
21356249 - Lesions of the dorsal lateral septum do not affect neophagia in the novelty induced sup...
2912409 - Improved safety of glucagon testing for pheochromocytoma by prior alpha-receptor blocka...
17209919 - Evaluation of six presumptive tests for blood, their specificity, sensitivity, and effe...
21565719 - Armadillo armor: mechanical testing and micro-structural evaluation.
18770289 - A reverse transcriptase assay for the diagnosis of lymphoproliferative disease (lpd) of...
19378449 - Acceptability of hepatitis c virus testing methods among injecting drug users.
15022359 - Musculoskeletal stress markers in natufian hunter-gatherers and neolithic farmers in th...
7203729 - A simple nonparametric procedure: the maximin test.
24175129 - A proposed evidence-based shoulder special testing examination algorithm: clinical util...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  66     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-09-11     Completed Date:  1984-09-11     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  219-21     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / diagnosis
Adenoma / diagnosis
Colonic Neoplasms / diagnosis*
Humans
Occult Blood*
Reagent Kits, Diagnostic
Rectal Neoplasms / diagnosis*
Chemical
Reg. No./Substance:
0/Reagent Kits, Diagnostic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  [Agenesis of the gallbladder. A case report].
Next Document:  Severe para-aortic regurgitation due to ruptured congenital subaortic aneurysm. A case report.