Document Detail

Early detection of cerebral infarction and hypoxic ischemic encephalopathy in neonates using diffusion-weighted magnetic resonance imaging.
MedLine Citation:
PMID:  7824088     Owner:  NLM     Status:  MEDLINE    
Twelve newborn infants with clinical evidence of hypoxic ischemic brain injury had conventional and diffusion-weighted magnetic resonance imaging (MRI) performed one to six (median two) days and 7-42 days after birth. The extent and conspicuity of the early abnormalities was greater with diffusion-weighted than with conventional imaging in each of the four infants with neonatal infarction and in four of the infants with Grades II or III hypoxic ischemic encephalopathy (HIE). No abnormality was seen with either technique in the other four infants who had Grades I or II HIE. Diffusion weighted MRI may be important for the early diagnosis and grading of infants with hypoxic ischemic brain injury.
F M Cowan; J M Pennock; J D Hanrahan; K P Manji; A D Edwards
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuropediatrics     Volume:  25     ISSN:  0174-304X     ISO Abbreviation:  Neuropediatrics     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-02-14     Completed Date:  1995-02-14     Revised Date:  2008-01-16    
Medline Journal Info:
Nlm Unique ID:  8101187     Medline TA:  Neuropediatrics     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  172-5     Citation Subset:  IM    
Department of Paediatrics and Neonatal Medicine, Hammersmith Hospital, Royal Postgraduate Medical School, London, UK.
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MeSH Terms
Asphyxia Neonatorum / diagnosis*
Body Water / metabolism
Brain / pathology
Brain Damage, Chronic / diagnosis*
Cerebral Cortex / pathology
Cerebral Infarction / diagnosis*
Follow-Up Studies
Hypoxia, Brain / diagnosis*
Infant, Newborn
Magnetic Resonance Imaging / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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