| Early detection of cancer recurrence: 18F-FDG PET/CT can make a difference in diagnosis and patient care. | |
| | |
MedLine Citation:
|
PMID: 17204718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Early detection of recurrence is clinically important and can improve the prognosis and survival of patients with cancer. CT, considered the primary method of investigation because of its low cost and widespread availability, provides high-resolution anatomic details but may underestimate the actual tumor burden by overlooking small tumor clusters in areas of distorted anatomy after treatment. 18F-FDG PET is an effective whole-body imaging technique that detects metabolic changes preceding structural findings. However, the specificity of PET is impaired by false-positive or equivocal results attributable to the lack of precise anatomic landmarks and to sites of increased 18F-FDG uptake of nonmalignant etiology. PET/CT provides fused images that demonstrate the complementary roles of functional and anatomic assessments in the diagnosis of cancer recurrence through the precise localization of suspected 18F-FDG foci and their characterization as malignant or benign. In addition to the accurate diagnosis and definition of the whole extent of recurrent cancer, PET/CT has an impact on patient management because it can assist in defining potential candidates for surgery for cure, planning the appropriate surgical or radiotherapy approach, and referring patients with unresectable disease to other therapeutic options. |
| | |
Authors:
|
Ora Israel; Abraham Kuten |
Related Documents
:
|
17854148 - (18)f-dg pet/ct in detection of recurrence and metastasis of colorectal cancer. 18799318 - Preoperative staging of mesothelioma by 18f-fluoro-2-deoxy-d-glucose positron emission ... 12501018 - Staging of recurrent and advanced lung cancer with 18f-fdg pet in a coincidence techniq... 15717948 - Functional imaging in head and neck cancer. 17445738 - Neck and low back pain: neuroimaging. 12087438 - 3d volume rendering using multislice ct for dental implants. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Volume: 48 Suppl 1 ISSN: 0161-5505 ISO Abbreviation: J. Nucl. Med. Publication Date: 2007 Jan |
Date Detail:
|
Created Date: 2007-01-05 Completed Date: 2007-03-27 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0217410 Medline TA: J Nucl Med Country: United States |
Other Details:
|
Languages: eng Pagination: 28S-35S Citation Subset: IM |
Affiliation:
|
Department of Nuclear Medicine, Rambam Health Care Campus, Haifa, Israel. o_israel@rambam.health.gov.il |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Fluorodeoxyglucose F18
/
diagnostic use* Humans Neoplasm Recurrence, Local / diagnosis*, prevention & control Neoplasms / diagnosis*, therapy Positron-Emission Tomography / methods* Prognosis Radiopharmaceuticals / diagnostic use Reproducibility of Results Risk Assessment / methods* Risk Factors Sensitivity and Specificity Subtraction Technique Systems Integration Technology Assessment, Biomedical Tomography, X-Ray Computed / methods* Treatment Outcome Whole Body Imaging / methods* |
| Chemical | |
Reg. No./Substance:
|
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Integrating PET and PET/CT into the risk-adapted therapy of lymphoma.
Next Document: Monitoring cancer treatment with PET/CT: does it make a difference?