| "Early death" and the contraindication of vaccine during treatment of rabies. | |
| | |
MedLine Citation:
|
PMID: 19925949 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Administration of rabies vaccine or rabies immune globulin (RIG) during symptomatic rabies is ineffective, and there are concerns about the phenomenon of "early death" reported in animals that develop rabies after receipt of rabies vaccine or immune globulin. Survival analyses of the original animal data confirm these findings in two species, whereas analyses of human case reports and the Milwaukee Protocol registry suggest lower risk of "early death" in humans. There may be a deleterious interaction of rabies vaccine and RIG with bat rabies in humans. Animal studies of bat rabies virus with bat-origin vaccines and RIG are urgently needed. |
| | |
Authors:
|
Rodney E Willoughby |
Related Documents
:
|
18572649 - Basic fibroblast growth factor loaded biodegradable pcl-peg-pcl copolymeric nanoparticl... 17646909 - Adverse effects of rabies pre- and postexposure prophylaxis in 290 health-care-workers ... 16878469 - Epidemiological analysis of setbacks in oral vaccination in the final stage of fox rabi... 3665969 - Scintigraphic evaluation of enterogastric reflux using 75se-hcat: methodology and first... 11878829 - A mixed ectoparasite--microparasite model for bat-transmitted rabies. 9112829 - Study of the swelling capacity of a mild laxative formulation. 11257339 - Pneumococcal infection and vaccination in the elderly. 23683999 - Evaluation of the immune response elicited by vaccination with viral vectors encoding f... 23390249 - Lineage structure of the human antibody repertoire in response to influenza vaccination. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Vaccine Volume: 27 ISSN: 1873-2518 ISO Abbreviation: Vaccine Publication Date: 2009 Nov |
Date Detail:
|
Created Date: 2009-11-20 Completed Date: 2010-01-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8406899 Medline TA: Vaccine Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 7173-7 Citation Subset: IM |
Affiliation:
|
Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI 53201-1997, USA. rewillou@mcw.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Humans Immunoglobulins / administration & dosage, adverse effects, contraindications* Kaplan-Meiers Estimate Post-Exposure Prophylaxis* Rabies / prevention & control*, therapy Rabies Vaccines / administration & dosage, adverse effects, contraindications* |
| Chemical | |
Reg. No./Substance:
|
0/Immunoglobulins; 0/Rabies Vaccines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluating the cost-effectiveness of rabies post-exposure prophylaxis: a case study in Tanzania.
Next Document: A robust lentiviral pseudotype neutralisation assay for in-field serosurveillance of rabies and lyss...