Document Detail


Early corneal findings in Cogan's syndrome.
MedLine Citation:
PMID:  6493698     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated the ocular manifestations of Cogan's syndrome in 13 consecutive patients. The most frequent and earliest ocular finding was bilateral peripheral subepithelial keratitis consisting of faint, nummular lesions. The subepithelial keratitis was responsive to topical administration of corticosteroids. Peripheral subepithelial keratitis was seen in four patients and strongly suspected on review of history in three additional patients. Deep stromal keratitis was seen in two patients, while only one patient developed classic findings of Cogan's syndrome, ie. interstitial keratitis with vascularization. Additionally, five patients presented with noncorneal ocular inflammatory disease and deafness (atypical Cogan's syndrome). Early subepithelial keratitis in Cogan's syndrome may be mistakenly diagnosed as trival ocular inflammatory disease, and suppressed by topical corticosteroids, resulting in delayed diagnosis of Cogan's syndrome in the absence of classic corneal findings. Early diagnosis of Cogan's syndrome is important inasmuch as prompt treatment of cochlear symptoms with systemic corticosteroids may prevent or ameliorate deafness.
Authors:
L M Cobo; B F Haynes
Related Documents :
9372688 - The comet-tail artifact. an ultrasound sign of alveolar-interstitial syndrome.
7197678 - Bone fusion in the foetal alcohol syndrome.
3598118 - Rett's syndrome: progression of symptoms from infancy to childhood.
19950078 - Length of the styloid process and anatomical implications for eagle's syndrome.
10463978 - Paraneoplastic syndromes in patients with hepatocellular carcinoma in taiwan.
21344638 - Clinical, pathological, and molecular analyses of cardiovascular abnormalities in coste...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmology     Volume:  91     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-11-28     Completed Date:  1984-11-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  903-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cornea / pathology
Deafness / complications,  diagnosis
Female
Humans
Keratitis / complications,  etiology*,  pathology
Male
Middle Aged
Syndrome
Vertigo / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Letter legibility and the construction of a new visual acuity chart.
Next Document:  Dominant optic atrophy, deafness, ptosis, ophthalmoplegia, dystaxia, and myopathy. A new syndrome.