Document Detail

Early congenital syphilis still occurs.
MedLine Citation:
PMID:  3841473     Owner:  NLM     Status:  MEDLINE    
Seven cases of early congenital syphilis have been recorded in the past 10 years in the Mersey Regional Health Authority. Antenatal serology was initially negative in five mothers, who were either incubating or acquired the infection later, and treatment had probably failed in two women given erythromycin for syphilis during pregnancy. Serology should be repeated later in pregnancy in those at high risk. Social factors that define this group include women who book for antenatal care late in pregnancy, have a past history of sexually transmitted disease, and have multiple consorts. Clinical signs in the infant such as failure to thrive, hepatosplenomegaly, symmetrical rash, rhinitis, and osteochondritis should alert the clinician to the possibility of congenital syphilis. Adequate management of mother and baby requires close liaison between the genitourinary physician, microbiologist, obstetrician, and paediatrician. Penicillin remains the treatment of choice.
C I Ewing; C Roberts; D C Davidson; O P Arya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  60     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1985 Dec 
Date Detail:
Created Date:  1986-03-07     Completed Date:  1986-03-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1128-33     Citation Subset:  AIM; IM    
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MeSH Terms
Erythema / etiology
Infant, Newborn
Maternal-Fetal Exchange
Social Conditions
Syphilis / transmission
Syphilis Serodiagnosis
Syphilis, Congenital / complications,  diagnosis*

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