Document Detail


Early complications and value of initial clinical and paraclinical observations in victims of smoke inhalation without burns.
MedLine Citation:
PMID:  9118707     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the incidence of early pulmonary complications and the value of initial clinical signs and paraclinical investigations in victims of smoke inhalation not suffering from burns following structural fires. DESIGN: Retrospective chart review. SETTING: Thirteen-bed ICU. PATIENTS: Sixty-four victims of smoke inhalation following household fires were admitted to the ICU between January 1987 and December 1992. Exclusion criteria from the study were patients with cutaneous burns or multiple trauma or blast injury, and patients found in cardiac arrest. METHODS: Clinical, biological, and radiologic parameters were collected over a 5-day period. RESULTS: The mortality rate in relation to progressive respiratory failure was 3.1%. Mean ICU stay was 5.8 days (range, 1 to 33 days), and was longer in the patients presenting with soot deposits in the oropharynx (p = 0.02), dysphonia (D) (p = 0.05), or ronchi (R) (p = 0.0004) at the first examination, and in those having a positive sputum bacteriologic analysis (p = 0.003) or requiring parenteral bronchodilator agents for more than 24 h (p = 0.04). Thirty-five patients underwent mechanical ventilation (MV) for a mean of 101.2 h (range, 8 to 648 h). Mean MV duration was higher in the patients presenting initially with R (p = 0.003), high carbon monoxide (but not cyanide) levels (p = 0.02), or a positive bacteriologic sample (p = 0.0001). Positive bacteriologic sampling correlated with the presence of D (p = 0.02) or R (p = 0.04) and with immediate intubation (p = 0.0003). No correlation was found with chest radiograph. CONCLUSIONS: In this selected series of fire victims without cutaneous burns, respiratory injury was frequent. The initial clinical signs may be helpful to predict pulmonary complications.
Authors:
P Hantson; R Butera; J L Clemessy; A Michel; F J Baud
Related Documents :
12615457 - Peripheral blood lymphocytes immunophenotype and serum concentration of soluble hla cla...
22294777 - Proof-of-principle study to detect metabolic changes in peritoneal dialysis effluent in...
10507597 - Myocardial cell injury in septic shock.
377467 - Warm dry air treatment of 345 patients with burns exceeding 20 per cent of the body sur...
15489407 - Electro-oculographic measures in patients with chronic whiplash and healthy subjects: a...
454097 - The outcome of behavior therapy for agoraphobia in relation to marital adjustment.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  111     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-04-24     Completed Date:  1997-04-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  671-5     Citation Subset:  AIM; IM    
Affiliation:
Service du Pr Favre-Bismuth, Hopital Fernand Widal, Université Paris VII, France. hantson@rean.ucl.ac.be
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Bronchi / pathology
Bronchoscopy
Female
Humans
Intensive Care
Length of Stay
Male
Middle Aged
Oropharynx / pathology
Respiration, Artificial
Respiratory Insufficiency / etiology
Retrospective Studies
Smoke Inhalation Injury / complications*,  microbiology,  pathology,  therapy
Sputum / microbiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of bi-level positive airway pressure (BiPAP) nasal ventilation on the postoperative pulmonary...
Next Document:  Impact of BAL data on the therapy and outcome of ventilator-associated pneumonia.