| Early clinical experience with the new Amplatzer Ductal Occluder II for closure of the persistent arterial duct. | |
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MedLine Citation:
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PMID: 19360878 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To describe the early single-center clinical experience with the Amplatzer Ductal Occluder II (ADO II). METHODS: All patients undergoing attempted transcatheter closure of persistent arterial duct (PDA) with the ADO II were included. Data collected included demographic, clinical, and echocardiographic parameters. RESULTS: From March until September 2008, 29 procedures were undertaken in 27 patients (21 female). Median age was 1.4 years (range 0.4-76 years) with median weight 9.4 kg (range 4.7-108 kg). A transarterial approach was used in 2 patients. The median minimum ductal diameter was 2.7 mm (range 1.7-5). ADO II was released in 25 patients (92.5%). Two patients had significant residual shunting following deployment of ADO II and underwent closure with Amplatzer ductal occluder (ADO I). Postprocedural echocardiography identified one occluder had changed position with development of a significant leak and one occluder had embolized to the left pulmonary artery. Both occluders were retrieved successfully at a second catheter procedure. Complete occlusion was noted predischarge in 22 of the remaining 23 occluders (96%). One patient had mild flow acceleration in the left pulmonary artery which has resolved. CONCLUSIONS: The ADO II is highly effective at providing rapid occlusion of morphologically varied PDAs. Occluder design allows closure with arterial or venous approach and delivery with 4 or 5 F delivery catheters. Stable occluder position is dependent on correct positioning of both aortic and pulmonary discs. A larger range of sizes and configurations of this occluder may be required to successfully occlude all ductal sizes and morphologies. |
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Authors:
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Jonathan Forsey; Damien Kenny; Gareth Morgan; Alison Hayes; Mark Turner; Andrew Tometzki; Robin Martin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: 74 ISSN: 1522-726X ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-05 Completed Date: 2009-12-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: United States |
Other Details:
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Languages: eng Pagination: 615-23 Citation Subset: IM |
Affiliation:
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Bristol Congenital Heart Centre, University Hospitals Bristol, NHS Foundation Trust, Bristol, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Balloon Occlusion / adverse effects, instrumentation* Child Child, Preschool Ductus Arteriosus, Patent / physiopathology, radiography, therapy*, ultrasonography Female Heart Catheterization / adverse effects, instrumentation* Hemodynamics Humans Infant Male Patient Selection Prosthesis Design Retrospective Studies Septal Occluder Device* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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