Document Detail

Early clinical experience with a modified Amplatzer ductal Occluder for transcatheter arterial duct occlusion in infants and small children.
MedLine Citation:
PMID:  22718329     Owner:  NLM     Status:  Publisher    
OBJECTIVES: To describe early clinical experience with the Amplatzer Ductal Occluder II Additional Sizes (ADO II AS) for percutaneous arterial duct occlusion in infants and small children. METHODS: Pre-, intra- and post-procedural data analysis of all patients undergoing arterial duct occlusion with the ADO II AS from three tertiary referral centers. RESULTS: 17 patients (10 female) with a median age of 6 months (range1.0-48.1 months) and a median weight of 5.7 kgs (range 1.7-17.4 kgs) underwent attempted transcatheter ductal closure with the ADO II AS. Retrograde arterial approach was used in 8 patients with transvenous femoral approach used in 9. The mean minimal ductal diameter was 2.2±0.7 mm with mean ductal length of 6.8±1.7 mm. Device sizes used were 5/6 (n=5), 3/4 (n=4), 4/4 (n=3), 4/6 (n=3), and 5/4 (n=2) with 4 French delivery sheaths used in all cases. The median fluoroscopy time was 5.7±1.8 minutes. Two patients underwent delivery under exclusive echocardiography guidance. Complete ductal occlusion was achieved by the end of the procedure in 13 patients. Device embolization to the left pulmonary artery occurred in one patient with successful surgical removal and ligation of the arterial duct. Three patients required device resizing following deployment of the initial device. Complete ductal occlusion without aortic arch or left pulmonary artery stenosis has been identified in all 16 remaining patients on transthoracic echocardiographic follow-up at median of 4.2 months. CONCLUSIONS: The new Amplatzer Ductal Occluder II AS achieves excellent ductal closure rates through low profile delivery systems in small infants and children with variable ductal anatomy. © 2012 Wiley Periodicals, Inc.
Damien Kenny; Gareth J Morgan; James R Bentham; Neil Wilson; Robin Martin; Andreww Frcp; Paul Oslizlok; Kevin P Walsh
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-21
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  -     ISSN:  1522-726X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Consultant Pediatric Cardiologist, Cardiac Department, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
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