| Early catastrophic stentless valve failure secondary to possible immune reaction. | |
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MedLine Citation:
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PMID: 21440160 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Aortic valve replacement with stentless xenografts has become routine since their introduction in the early 1990s. Although concerns of structural valve deterioration and long-term durability have been voiced, the reports on the causes or pathology associated with early valve failure have been sparse. We report two unusual cases of failure leading to patient death within the first year after implantation of the aortic valve and root with the Freestyle prostheses (Medtronic Inc, Minneapolis, MN). We suggest an early immunologic reaction to the xenograft, leading to a fatal inflammatory process, as a mechanism for unusual early valve failure in these patients. |
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Authors:
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Kathryn L O'Keefe; Stephen D Cohle; Jeremiah E McNamara; Robert L Hooker |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 91 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1269-72 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of General Surgery, Grand Rapids Medical Education Partners, Grand Rapids, Michigan. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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