Document Detail


Early blood exchange transfusion in malignant pertussis: A case report.
MedLine Citation:
PMID:  20921917     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: : To report early blood exchange transfusion in malignant pertussis and a favorable clinical outcome.
SETTING: : A pediatric intensive care unit in a tertiary hospital in Geneva, Switzerland.
DESIGN: : A descriptive case report.
PATIENT: : An 8-wk-old girl was diagnosed with malignant pertussis (extreme leukocytosis, seizures, pneumonia, and secondary severe hypoxic respiratory failure associated with pulmonary hypertension). After administration of a one-volume blood exchange transfusion, a rapid decrease in white blood cell count (from 119,000/mm to 36,500/mm) was observed and followed by clinical improvement and favorable outcome despite the initial presence of all described risk factors associated with a high mortality.
CONCLUSION: : The use of exchange blood transfusion early in the course of the disease might help to prevent a fatal outcome of malignant pertussis.
Authors:
Manuel Martinez; Isabelle Rochat; Regula Corbelli; Pierre Tissières; Peter C Rimensberger; Constance Barazzone-Argiroffo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  12     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-06-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e107-9     Citation Subset:  IM    
Affiliation:
From the Department of Pediatrics (MM), Pulmonology Unit, Pediatric Pulmonology Unit (IR, RC, CA-B), and Pediatric Intensive Care Unit (PT, PCR), University Hospital of Geneva, Geneva, Switzerland.
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