Document Detail


Early assessment of renal resistance index and long-term renal function in renal transplant recipients.
MedLine Citation:
PMID:  19142805     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The effect of the intrarenal arterial resistance index (RI) on long-term renal functions is not well known. We examined the predictive value of intrarenal RI on long-term allograft outcomes. METHODS: We retrospectively investigated 121 stable renal transplant recipients, followed for a mean of 63.21 +/- 19.9 months after renal transplant. Patients with complications during the first six months after transplant were not included. Color Doppler ultrasonography was done to calculate the intrarenal RI within the first four weeks after transplant. RESULTS: Older recipient age, high pulse pressure, active smoking, and proteinuria were associated with a higher intrarenal RI. Multivariate analyses revealed that renal RI and donor age were independent predictors of allograft outcome. Kaplan-Meier estimates of cumulative graft survival were significantly worse in patients who had an RI of 0.7 or more than they were in patients who had an RI of less than 0.7 (p = .005). Development of chronic allograft nephropathy (CAN) was significantly higher in patients who had an RI of 0.7 or more (p = .02). CONCLUSIONS: Renal RI determined within the first month after renal transplant predicts long-term allograft function and development of CAN in renal transplant recipients.
Authors:
Arzu Akgul; Avsin Ibis; Siren Sezer; Ceyla Basaran; Alper Usluogullari; Fatma Nurhan Ozdemir; Zubeyde Arat; Mehmet Haberal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Renal failure     Volume:  31     ISSN:  1525-6049     ISO Abbreviation:  Ren Fail     Publication Date:  2009  
Date Detail:
Created Date:  2009-01-14     Completed Date:  2009-05-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  18-24     Citation Subset:  IM    
Affiliation:
Baskent University Faculty of Medicine, Department of Nephrology, Ankara, Turkey. arzuakgul@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Follow-Up Studies
Graft Survival
Humans
Kidney Failure, Chronic / physiopathology*,  surgery*,  ultrasonography
Kidney Transplantation*
Male
Middle Aged
Predictive Value of Tests
Renal Circulation / physiology*
Retrospective Studies
Time Factors
Treatment Outcome
Ultrasonography, Doppler, Color
Vascular Resistance / physiology*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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