Document Detail

Early arterial modifications in young patients with borderline hypertension.
MedLine Citation:
PMID:  2651613     Owner:  NLM     Status:  MEDLINE    
Pulse wave velocity, used as an indicator of arterial distensibility, was recorded in 123 young male subjects, 63 untreated patients with borderline hypertension and 60 control subjects. The measurement was made with a continuous Doppler unit coupled to an ECG. In both groups mean age was similar, but mean arterial pressure was increased in borderline hypertensive compared with control patients. In comparison with controls, borderline hypertensives showed an increased pulse wave velocity. A significant correlation was observed between mean arterial pressure and pulse wave velocity in both populations, but the two regression lines were significantly different (covariance analysis). This result suggests that pulse wave velocity modifications in borderline hypertensives are not solely due to the elevated pressure, but also reflect structural or functional changes in the arterial tree.
X Girerd; X Chanudet; P Larroque; R Clement; B Laloux; M Safar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of hypertension. Supplement : official journal of the International Society of Hypertension     Volume:  7     ISSN:  0952-1178     ISO Abbreviation:  J Hypertens Suppl     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-06-01     Completed Date:  1989-06-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501422     Medline TA:  J Hypertens Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S45-7     Citation Subset:  IM    
Diagnostic Centre of Broussais Hospital, Paris, France.
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MeSH Terms
Blood Flow Velocity
Blood Pressure
Heart Rate
Hypertension / physiopathology*
Muscle, Smooth, Vascular / physiopathology*

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