| Early amniocentesis with the filtration technique: neonatal outcome in 123 singleton pregnancies. | |
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MedLine Citation:
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PMID: 12378565 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate results of a prospective study of pregnancies in which early amniocentesis with the filtration technique was performed at 10-13 weeks' gestation (mean 12.3 weeks' gestation). METHODS: 123 singleton pregnancies in which early amniocentesis with the modified filtration technique was performed at 10-13 weeks' gestation (mean 12.3 weeks' gestation). The amniotic fluid was aspirated into the syringe and reinjected through the filter. RESULTS: All the procedures were performed successfully by a single needle insertion. Neither dry taps nor filtration failures occurred. The mean time of amniocentesis was 4.02 min (95% confidence interval, 3 min and 36 s to 4 min and 18 s). The karyotyping success rate was 99.2%. Temporary amniotic fluid leakage occurred in three women (2.4%). There were 110 (89.4%) live births. Two cases of stillbirth occurred at week 38 and week 40. Two unintended losses occurred within three weeks after sampling (1.62%). Another additional unintended fetal death was notified at the 20-week screening ultrasonography. The total fetal-loss rate was 10.6%. In one case, talipes equinovarus was detected at the 20-week screening ultrasound study. CONCLUSIONS: Further studies are needed to determine the risk of amniotic leakage and its relation to duration of the procedure in patients undergoing early amnifiltration. |
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Authors:
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I Farrán; M A Sánchez; C Mediano; A Plaja; A Guzmán; A M de la Riva; L Cabero |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Prenatal diagnosis Volume: 22 ISSN: 0197-3851 ISO Abbreviation: Prenat. Diagn. Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2002-10-14 Completed Date: 2002-12-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8106540 Medline TA: Prenat Diagn Country: England |
Other Details:
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Languages: eng Pagination: 859-63 Citation Subset: IM |
Copyright Information:
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Copyright 2002 John Wiley & Sons, Ltd. |
Affiliation:
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Unit of Prenatal Diagnosis, Hospital Universitari Vall d'Hebron, Universitat Autónoma de Barcelona, Passeig de la Vall d'Hebron 119-129, E-08035 Barcelona, Spain. ifarranc@meditex.es |
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| MeSH Terms | |
Descriptor/Qualifier:
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Amniocentesis
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adverse effects,
instrumentation,
methods* Congenital Abnormalities / epidemiology, etiology Female Fetal Death / epidemiology, etiology Filtration* / instrumentation Gestational Age* Humans Infant, Newborn Karyotyping Pregnancy Pregnancy Outcome* |
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