| Early acute phase response following total hip replacement. | |
| | |
MedLine Citation:
|
PMID: 19828914 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The acute phase proteins are commonly known universal markers of the inflammatory process. The aim of the study was the evaluation of the acute phase response in the first 6 months THR. The secondary aim was to check if the type of hip replacement affects the acute phase response. MATERIAL AND METHODS: The study group consisted of 40 patients who underwent THA using uncemented (20) and cemented (20) endoprostheses. The concentrations of C-reactive protein, alpha-glycoprotein, and alpha-1-antichymotripsin, and microheterogeneity of AGP were evaluated. RESULTS: The blood levels of the acute phase proteins CRP, AGP, ACT rose significantly at 2 and 14 days after the surgery to return to preoperative values at 6 months after the surgery. The V3 variant of microheterogeneity of AGP, absent under normal conditions, and representative of acute inflammation, was found in a few patients preoperatively. In postoperative evaluations, it was found in the vast majority of the patients. CONCLUSIONS: The analysis of the profiles of the glycosylation of AGP shows that the presence of the acute inflammatory response immediately following total hip replacement, which later changes into persistent chronic inflammation, is more pronounced in patients receiving cemented endoprosthesis. |
| | |
Authors:
|
Jacek Markuszewski; Ma??gorzata Wierusz-Koz??owska; Waldemar Wo??niak; Kinga Le??niewska; Magdalena Sobieska |
Related Documents
:
|
17106714 - Rofecoxib inhibits heterotopic ossification after total hip arthroplasty. 15067644 - Treatment of recurrent dislocation of total hip arthroplasty using a ligament prosthesis. 18812894 - Early outcomes after hip arthroscopy for femoroacetabular impingement in the athletic a... 954324 - Congenital hip dysplasia in the light of early and very early diagnosis. 23017254 - Differential effect of nutritional status on vascular surgery outcomes in a veterans af... 23257934 - Mortality rate in bullous pemphigoid: a retrospective monocentric cohort study. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Ortopedia, traumatologia, rehabilitacja Volume: 11 ISSN: 1509-3492 ISO Abbreviation: - Publication Date: 2009 Jul-Aug |
Date Detail:
|
Created Date: 2009-10-15 Completed Date: 2010-01-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101240146 Medline TA: Ortop Traumatol Rehabil Country: Poland |
Other Details:
|
Languages: eng; pol Pagination: 324-32 Citation Subset: IM |
Affiliation:
|
Department of General Surgery, Orthopaedics and Traumatology, Karol Marcinkowski University of Medical Sciences, Pozna??, Poland. jmarkuszewski@orsk.ump.edu.pl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Acute-Phase Proteins / analysis* Acute-Phase Reaction / etiology* Adult Aged Analysis of Variance C-Reactive Protein / analysis Female Glycoproteins / blood Hip Prosthesis / adverse effects* Humans Male Middle Aged Osteoarthritis, Hip / immunology, surgery Poland Transferrin / analysis alpha 1-Antichymotrypsin / blood |
| Chemical | |
Reg. No./Substance:
|
0/Acute-Phase Proteins; 0/Glycoproteins; 0/alpha 1-Antichymotrypsin; 11096-37-0/Transferrin; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Initial experience with short Metha stem implantation.
Next Document: OUTCOMES OF COMBINED HAMSTRING RELEASE AND RECTUS TRANSFER IN CHILDREN WITH CROUCH GAIT.