Document Detail


Early results of rheolytic thrombectomy in patients with proximal deep vein thrombosis.
MedLine Citation:
PMID:  21597205     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The utility of rheolytic thrombectomy as a treatment for proximal deep vein thrombosis (DVT) is not well understood.
METHODS AND RESULTS: Patients with proximal DVT were treated with rheolytic thrombectomy, and the safety and efficacy of the procedure were evaluated. The improvement of venous thrombi was assessed using the venographic segment (VS) score. The rheolytic rate was defined as the percentage thrombus aspiration achieved. We also evaluated whether there were differences in age, aspiration time, D-dimer concentration, or the duration from onset to therapy between the high and low rheolytic rate groups. The mean VS score before thrombectomy was 28.8 ± 7.9 points, and the mean VS score after thrombectomy was 10.4 ± 7.1 points (ie, the VS score was significantly decreased after thrombectomy). There were no major treatment-related adverse complications. The mean duration from onset to rheolytic therapy in the 4 patients with a low rheolytic rate was 13.5 ± 13.2 days, which was much longer than for the 9 patients with a high rheolytic rate (mean duration: 4.0 ± 2.2 days: P = 0.045).
CONCLUSIONS: Rheolytic thrombectomy is safe and effective for treating proximal DVT. The duration from onset to therapy was the only factor that was significantly predictive of the outcome of rheolytic thrombectomy. Rheolytic thrombectomy was especially effective when performed within 1 week of onset.
Authors:
Akihiro Tsuji; Norikazu Yamada; Satoshi Ota; Ken Ishikura; Mashio Nakamura; Masaaki Ito
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2011-05-20
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  75     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2011  
Date Detail:
Created Date:  2011-06-24     Completed Date:  2012-01-18     Revised Date:  2012-01-26    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1742-6     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Mie University Graduate School of Medicine, Tsu, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Female
Humans
Male
Middle Aged
Phlebography
Plethysmography / adverse effects,  methods*
Predictive Value of Tests
Retrospective Studies
Thrombectomy / adverse effects,  methods*
Time Factors
Treatment Outcome
Venous Thrombosis / radiography,  surgery*

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