Document Detail


Early Neonatal Intensive Care Unit Therapy Improves Predictive Power for the Outcomes of Ventilated Extremely Low Birth Weight Infants.
MedLine Citation:
PMID:  21429509     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To assess the predictive value of early therapy for ventilated extremely low birth weight (ELBW) infants beyond information available at delivery. STUDY DESIGN: Prospective, single-center cohort analysis of 177 ventilated ELBW infants. We collected information known at delivery (gestational age, birth weight, singleton, sex, antenatal steroids) and additional information while infants were mechanically ventilated (head ultrasound scanning, clinician intuitions of death before discharge). An adverse outcome was defined as mortality or Bayley Mental Developmental Index or Psychomotor Developmental Index <70 at 2 years. We compared the predictive ability of clinical variables separately, in combination, and in addition to information available at delivery. RESULTS: A total of 77% of infants survived to follow-up; 56% of survivors had Bayley Mental Developmental Index and Psychomotor Developmental Index ≥70. A total of 95% of infants with both abnormal head ultrasound scanning results and predicted death before discharge had an adverse outcome, independent of gestational age. Conversely, 40% of infants with normal head ultrasound scanning results and no predicted death before discharge had an adverse outcome, independent of gestational age. After adjusting for variables known at birth, predicted death before discharge and abnormal head ultrasound scanning results added significantly to the ability to predict outcomes. CONCLUSION: Information gained early in the neonatal intensive care unit improves prediction of mortality or neurodevelopmental impairment in ventilated ELBW infants beyond information available in the delivery room.
Authors:
Joanne Lagatta; Bree Andrews; Leslie Caldarelli; Michael Schreiber; Susan Plesha-Troyke; William Meadow
Related Documents :
9825599 - Is maternal malnutrition associated with a low sex ratio at birth?
12047579 - Analysis of the influence of diurnal variation in maternal movements on fetal heart rat...
16343339 - National estimates for maternal mortality: an analysis based on the who systematic revi...
738829 - Projective identification and maternal impingment.
2134779 - A comparison of adolescent and adult mothers on factors affecting maternal role attainm...
10871589 - Maternal mortality in the past and its relevance to developing countries today.
22315809 - A comparative study of brainstem auditory evoked potentials in preterm and full-term in...
47079 - Passive transfer of antibodies of maternal origin from blood to cerebrospinal fluid in ...
281099 - Monitoring of fetuses with retarded bpd growth.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-21
Journal Detail:
Title:  The Journal of pediatrics     Volume:  -     ISSN:  1097-6833     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Mosby, Inc. All rights reserved.
Affiliation:
Department of Pediatrics, University of Chicago, Chicago, IL.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prevalence of Cardiometabolic Risk Factor Clustering and Body Mass Index in Adolescents.
Next Document:  Characteristics of hospitalizations for patients who use a structured clinical care program for chil...