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Early Intervention for First-episode Psychosis in India.
MedLine Citation:
PMID:  23019281     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE. There have been very few studies of first-episode psychoses or early intervention programmes in India. This paper describes a pilot intervention programme for first-episode psychosis at the Schizophrenia Research Foundation, India. METHODS. A total of 47 patients with the first episode of psychosis were followed up for 2 years. Based on the Positive and Negative Syndrome Scale for schizophrenia and Global Assessment of Functioning Scale scores, the data from 2 groups of patients, those who had remission and those who did not, were identified and compared. Assessments done at 3, 6, 12 and 24 months after recruitment enabled computation of time to achieve remission. RESULTS. Complete data were available for 38 patients (28 patients in remission group and 10 patients in non-remission group) at 2 years. Baseline scores were not significantly different between the groups. In the remission group, more than 50% attained maximal improvement at 3 months, another 30% at 1 year, and the remaining 20% at 2 years. Maximal reduction in the mean Positive and Negative Syndrome Scale score was seen between 3 and 6 months after recruitment. CONCLUSIONS. With regular treatment, most patients with early psychosis achieve remission within 2 years. Negative symptoms persisting for longer than 6 months could be an indicator of long-term outcome. Early intervention is feasible and effective in developing countries.
T Rangaswamy; R Mangala; G Mohan; J Joseph; S John
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan     Volume:  22     ISSN:  2224-7041     ISO Abbreviation:  East Asian Arch Psychiatry     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101536416     Medline TA:  East Asian Arch Psychiatry     Country:  China    
Other Details:
Languages:  eng     Pagination:  94-9     Citation Subset:  IM    
Schizophrenia Research Foundation, India.
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