Document Detail


Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient.
MedLine Citation:
PMID:  9436850     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.
Authors:
S Menni; G Pistritto; R Gianotti; L Ghio; A Edefonti
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  14     ISSN:  0736-8046     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    1997 Nov-Dec
Date Detail:
Created Date:  1998-02-24     Completed Date:  1998-02-24     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  477-9     Citation Subset:  IM    
Affiliation:
Istituto di Scienze Dermatologiche, Clinica pediatrica II, Università degli Studi di Milano, Milan, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adjuvants, Immunologic / adverse effects*,  therapeutic use
Arterial Occlusive Diseases / chemically induced*
Biopsy
Child
Ear, External / blood supply,  pathology*
Humans
Levamisole / adverse effects*,  therapeutic use
Necrosis
Nephrotic Syndrome / drug therapy
Skin / blood supply
Skin Diseases, Vesiculobullous / chemically induced*,  pathology
Vasculitis / chemically induced*,  pathology
Chemical
Reg. No./Substance:
0/Adjuvants, Immunologic; 14769-73-4/Levamisole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Netherton syndrome presenting as congenital psoriasis.
Next Document:  Current options for the topical treatment of acne vulgaris.