Document Detail

EUS in the management of uninvestigated dyspepsia.
MedLine Citation:
PMID:  12447295     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Management of dyspepsia often involves multiple diagnostic tests. By virtue of luminal and extraluminal imaging, EUS may be a satisfactory single test for the evaluation of patients with dyspepsia. METHODS: Patients with uninvestigated dyspepsia of more than 4 weeks duration were recruited. All underwent transabdominal US followed by EUS and EGD to look for both luminal and extraluminal lesions that could account for the dyspeptic symptoms. Each of these studies was performed by an independent operator blinded to the results of the other examinations. Patients were followed for 1 year to monitor clinical outcome. RESULTS: Two hundred patients were recruited. Compared with EGD, EUS had accuracies of 92% to 100% for the diagnosis of different luminal lesions. All gastric ulcers and cancers were detected by EUS, but 3 duodenal ulcers were missed. EUS also identified 48 pancreaticobiliary lesions, 23 of which were detected by US, that could account for the dyspeptic symptoms. Other extraintestinal lesions including mediastinal malignant lymphadenopathy and a dissecting aortic aneurysm were also diagnosed by EUS. Through the identification of extraluminal lesions, staging of tumors, and exclusion of pancreaticobiliary diseases, EUS altered clinical management in 50 patients (25%). CONCLUSION: EUS is a useful one-step investigation in patients with dyspepsia.
Yuk Tong Lee; Alex C W Lai; Yui Hui; Justin C Y Wu; Vincent K S Leung; Francis K l Chan; S C Sydney Chung; Joseph J Y Sung
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gastrointestinal endoscopy     Volume:  56     ISSN:  0016-5107     ISO Abbreviation:  Gastrointest. Endosc.     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-11-26     Completed Date:  2003-03-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0010505     Medline TA:  Gastrointest Endosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  842-8     Citation Subset:  IM    
Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, China.
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MeSH Terms
Aged, 80 and over
Cholelithiasis / ultrasonography
Digestive System Diseases / complications,  ultrasonography*
Duodenal Ulcer / ultrasonography
Dyspepsia / etiology,  ultrasonography*
Middle Aged
Predictive Value of Tests
Stomach Ulcer / ultrasonography
Comment In:
Am J Gastroenterol. 2003 Jul;98(7):1650-2   [PMID:  12873596 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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