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ETV for Idiopathic Aqueductal Stenosis.
MedLine Citation:
PMID:  22381825     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Idiopathic aqueductal stenosis is a cause of non communicating hydrocephalus which actual treatment by Endoscopic third ventriculostomy (ETV) could be assess without any interference with the etiology. The results of ETV in this indication could be therefore interpret as the results of the surgical procedure alone, without any additional factors related to the etiology of the CSF pathways obstruction like haemorrhage, infection, brain malformations and brain tumors or cysts. METHODS: Following a brief description of pathogenesis of hydrocephalus in aqueductal stenosis, the authors review the literature for studies on ETV, extrapolating patients with idiopathic aqueductal stenosis in infancy, childhood and adulthood. Differences in outcome between patients treated with ETV and patients treated with ventriculo-peritoneal shunt (VPS) are also reviewed. RESULTS: The overall success rates of ETV ranges between 23% to 94% , with a mean of 68%; when only patients affected by obstructive tri-ventricular hydrocephalus secondary to aqueductal stenosis are considered, the success rate is actually quite homogeneous and stable, being above 60% at any age, even if a trend in lower success rate in very young infant (under 6 months of age) is noticeable. The few reports on intellectual outcome failed to demonstrate differences between ETV and VPS. CONCLUSION: Several issues, such as the cause of failures in well selected patients, long term outcome in infant treated with ETV, effect of persistent ventriculomegaly on neuropsychological developmental, remain unanswered. Larger and more detailed studies are needed.
Authors:
Pietro Spennato; Sanna Tazi; Olivier Bekaert; Giuseppe Cinalli; Philippe Decq
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-10
Journal Detail:
Title:  World neurosurgery     Volume:  -     ISSN:  1878-8750     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101528275     Medline TA:  World Neurosurg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
Affiliation:
Department of Pediatric Neurosurgery, Santobono-Paulipon Pediatric Hospital, Naples, Italy.
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