Document Detail


ESR studies of molecular interactions of copper(II) nirvanol and copper(II) diisopropylsalicylate with Ehrlich ascites tumor cells.
MedLine Citation:
PMID:  2830367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
ESR spectra have been obtained after addition of either a cupric phenylhydantoin or a cupric diisopropylsalicylate complex to Ehrlich ascites tumor cells. It is shown that some of the complex remains in the cupric state. Because the ESR parameters of these complexes in the presence of cells differ from the ESR parameters for these complexes in the absence of cells, in the presence of cells either adducts or new cupric complexes are formed. The fast motion of these complexes, as determined from room temperature ESR spectra, is characteristic of complexes with molecular weights less than 1500.
Authors:
A Pezeshk; W E Antholine; D H Petering
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of inorganic biochemistry     Volume:  31     ISSN:  0162-0134     ISO Abbreviation:  J. Inorg. Biochem.     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-04-06     Completed Date:  1988-04-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7905788     Medline TA:  J Inorg Biochem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  283-91     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Moorhead State University, Milwaukee, WI.
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MeSH Terms
Descriptor/Qualifier:
Animals
Carcinoma, Ehrlich Tumor / metabolism*
Chemical Phenomena
Chemistry
Electron Spin Resonance Spectroscopy / methods
Hydantoins / chemical synthesis,  metabolism*
Mice
Organometallic Compounds / chemical synthesis,  metabolism*
Salicylic Acids / metabolism*
Grant Support
ID/Acronym/Agency:
CA22184/CA/NCI NIH HHS; GM35472/GM/NIGMS NIH HHS; RR01008/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Hydantoins; 0/Organometallic Compounds; 0/Salicylic Acids; 113032-60-3/bis(5-ethyl-5-phenylhydantoin)bispyridine Cu(II); 21246-18-4/copper bis(3,5-diisopropylsalicylate)

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