Document Detail


ESCRT machinery and cytokinesis: the road to daughter cell separation.
MedLine Citation:
PMID:  21722282     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Endosomal Sorting Complex Required for Transport (ESCRT) machinery is a set of cellular protein complexes required for at least three topologically equivalent membrane scission events, namely multivesicular body (MVBs) formation, retroviral particle release and midbody abscission during cytokinesis. Recently, several studies have explored the mechanism by which the core ESCRT-III subunits mediate membrane scission and might be differentially required according to the functions of the pathway. In this review, we discuss the links between the ESCRT machinery and cytokinesis, with special focus on abscission initiation and regulation.
Authors:
Anna Caballe; Juan Martin-Serrano
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-1
Journal Detail:
Title:  Traffic (Copenhagen, Denmark)     Volume:  -     ISSN:  1600-0854     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100939340     Medline TA:  Traffic     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 John Wiley & Sons A/S.
Affiliation:
Department of Infectious Diseases, King's College London School of Medicine, Guy's Hospital, London, SE1 9RT, UK.
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