Document Detail

EROD activity and biliary fluorescence in Schroederichthys chilensis (Guichenot 1848): biomarkers of PAH exposure in coastal environments of the South Pacific Ocean.
MedLine Citation:
PMID:  16168742     Owner:  NLM     Status:  MEDLINE    
Schroederichthys chilensis is a common shark that lives in Chilean coastal environments. In this work, the relationship between liver 7-ethoxyresorufin-O-deethylase dealkylation (EROD) activity and Fluorescent Aromatic Compounds (FAC) in bile of S. chilensis sampled in three bays with different degrees of pollution were performed including a reference area. Sixty individuals were collected, 20 for each site; (10 males and 10 females per site) livers and bile samples were obtained and immediately frozen. EROD activity and FAC were measured according to three standard methods. EROD activity and FAC were higher in polluted areas than in the reference area. Synchronous Fluorescence Spectra of the bile from the fish collected at the most polluted area showed a peak at 347nm representing a metabolite corresponding to 1-hydroxypyrene. The low EROD activity in the reference area is likely related to the low level of PAH in sediments. We propose that this species is a good indicator of exposure to FACs, since it presents a series of characteristics that make it suitable for monitoring PAH exposure in coastal zones.
Daniel Fuentes-Rios; Rodrigo Orrego; Anny Rudolph; Gonzalo Mendoza; Juan F Gavilán; Ricardo Barra
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemosphere     Volume:  61     ISSN:  0045-6535     ISO Abbreviation:  Chemosphere     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-19     Completed Date:  2005-11-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  England    
Other Details:
Languages:  eng     Pagination:  192-9     Citation Subset:  IM    
Faculty of Sciences, Department of Environmental Chemistry, Universidad Católica de la Santísima Concepción, P.O. Box 297, Concepción, Chile.
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MeSH Terms
Biological Markers / analysis*
Cytochrome P-450 CYP1A1 / metabolism*
Pacific Ocean
Polycyclic Hydrocarbons, Aromatic / poisoning*
Sharks / physiology*
Water Pollutants, Chemical / poisoning*
Reg. No./Substance:
0/Biological Markers; 0/Polycyclic Hydrocarbons, Aromatic; 0/Water Pollutants, Chemical; EC P-450 CYP1A1

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