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The EORTC Quality of Life Questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 Validation Study for Spanish patients.
MedLine Citation:
PMID:  21239355     Owner:  NLM     Status:  In-Data-Review    
Introduction The EORTC Quality of Life (QL) Group has developed a questionnaire -the EORTC QLQ-CR29- for evaluating QL in colorectal cancer. The aim of this study is to assess the psychometric properties of the EORTC QLQCR29 when applied to a sample of Spanish patients. Materials and methods Eighty-four locally advanced rectal cancer patients in the treatment follow-up period after receiving surgery and neoadjuvant chemoradiotherapy were included in the study. Seventy subjects also had adjuvant chemotherapy. Patients completed both the EORTC QLQC30 and the QLQ-CR29 once. The psychometric evaluation of the questionnaire's structure, reliability, and convergent, divergent and known-groups validity was performed. Results Multitrait scaling analysis showed that three of the multi-item scales met the standards of convergent and discriminant validity. These same scales reached the 0.7 Cronbach's coefficient criterion or were close to it. In both analyses exceptions were observed in the blood and mucus in stool scale. Correlations between the scales of the QLQC30 and the module were low (r<0.02) in most cases. A few areas with more related content had higher correlations (r<0.05). Group comparison analyses showed differences in QL between groups of patients based on age, comorbidity, performance status, receipt of adjuvant chemotherapy and surgery modality. Conclusions The EORTC QLQ-CR29 is a reliable and valid instrument when applied to a sample of Spanish rectal cancer patients. These results are in line with those of the EORTC validation study.
J I Arraras; J Suárez; F Arias de la Vega; R Vera; G Asín; V Arrazubi; M Rico; L Teijeira; J Azparren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico     Volume:  13     ISSN:  1699-3055     ISO Abbreviation:  Clin Transl Oncol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101247119     Medline TA:  Clin Transl Oncol     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  50-6     Citation Subset:  IM    
Radiotherapeutic Oncology Department, Hospital de Navarra, Pamplona, Navarra, Spain.
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