| EMPACT syndrome. | |
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MedLine Citation:
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PMID: 21675930 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Phenytoin is commonly used an antiepileptic medication for seizure prophylaxis in patients with brain metastases. In these oncology patients group, phenytoin-induced severe adverse reactions may occur. Antiepileptic, particularly phenytoin-induced severe skin reactions including Stevens-Johnson syndrome (SJS) and bullous form of erythema multiforme have been reported in the patients treated with cranial irradiation due to brain metastasis. The acronym EMPACT (Erythema Multiforme associated with Phenytoin And Cranial radiation Therapy) was recently described as a clinical entity. Herein, we report a 36-year-old female with breast carcinoma, who developed EMPACT syndrome after treating with cranial radiation therapy for brain metastasis and phenytoin for seizure prophylaxis. |
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Authors:
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Serap Gunes Bilgili; Omer Calka; Ayse Serap Karadag; Ahmet Zubeyir Burakgazi |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-16 |
Journal Detail:
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Title: Cutaneous and ocular toxicology Volume: - ISSN: 1556-9535 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101266892 Medline TA: Cutan Ocul Toxicol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Dermatology, Yuzuncu Yil University Faculty of Medicine, Van, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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