Document Detail


EMLA Cream coated on the rigid bronchoscope for tracheobronchial foreign body removal in children.
MedLine Citation:
PMID:  19117313     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Removal of a tracheal or bronchial foreign body is a common emergent surgical procedure in children. The anesthetic management can be challenging. EMLA Cream (EC) has been widely used to provide topical anesthesia. In the present study, we evaluate the efficacy and safety of EC coated on the rigid bronchoscope for tracheobronchial foreign body removal in children undergoing intravenous anesthesia with spontaneous ventilation. STUDY DESIGN: The authors conducted a randomized, double-blind, placebo-controlled clinical trial. METHODS: Thirty patients were randomized to receive either EC or placebo (lubricant ointment) coated on the rigid bronchoscope. Intravenous anesthesia and spontaneous ventilation were performed in all patients. Heart rate, blood pressure, pulse oxygen saturation (SpO(2)) and frequency and degree of breath holding were recorded. After surgery, the bronchoscopist rated overall surgical manipulation as excellent, fair, and poor. The durations of postoperative care were also recorded. RESULTS: Episodes of oxygen desaturation (SpO(2) < 90%) occurred in 3/15 (20%) patients in the EC group and in 9/15 (60%) patients in the control group (P < .05). Occurrences and degrees of breath holding were less in the EC group than that in the control group (P < .05). Ranks of surgical manipulation were excellent in 80% of patients in the EC group versus 13% of patients in the control group (P < .05). The durations of postoperative care were shorter in the EC group than that in the control group (P < .05). CONCLUSIONS: EC coated on the rigid bronchoscope combined with intravenous anesthesia could provide more efficacious and safer anesthesia for tracheobronchial foreign body removal in children under spontaneous ventilation.
Authors:
Hai Yu; Xiao-Yun Yang; Bin Liu
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Laryngoscope     Volume:  119     ISSN:  1531-4995     ISO Abbreviation:  Laryngoscope     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-22     Completed Date:  2009-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  158-61     Citation Subset:  IM    
Affiliation:
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Anesthetics, Local / administration & dosage*
Bronchi
Bronchoscopy*
Double-Blind Method
Female
Foreign Bodies / therapy*
Humans
Infant
Lidocaine / administration & dosage*
Male
Placebos
Prilocaine / administration & dosage*
Trachea
Chemical
Reg. No./Substance:
0/Anesthetics, Local; 0/EMLA; 0/Placebos; 137-58-6/Lidocaine; 721-50-6/Prilocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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