| EEG findings in heroin addicts during induction and maintenance on methadone. | |
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MedLine Citation:
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PMID: 50207 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study investigated changes in the EEG of addicts initially on heroin as they progressed through the induction and maintenance phases of a methadone program. Spectral analysis of bipolar recordings revealed significant consistent differences only in the eyes-closed resting state. Patients under the influence of heroin showed large sharp peaks at 9-10 c/sec, particularly in the parieto-occipital recording. Methadone induction led either to marked reduction of this peak and widening of alpha band activity or to an increase in frequency of the alpha peak to 12 c/sec. After several months of methadone the alpha peak was still absent unless heroin abuse was present, a theta peak was present in three of four patients, and the alpha bandwidth remained broad. Changes in the theta band were more difficult to interpret. |
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Authors:
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B Feinstein |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Electroencephalography and clinical neurophysiology Volume: 39 ISSN: 0013-4694 ISO Abbreviation: Electroencephalogr Clin Neurophysiol Publication Date: 1975 Jul |
Date Detail:
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Created Date: 1975-11-01 Completed Date: 1975-11-01 Revised Date: 2008-09-09 |
Medline Journal Info:
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Nlm Unique ID: 0375035 Medline TA: Electroencephalogr Clin Neurophysiol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 96-99 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Alpha Rhythm Cerebral Cortex / drug effects Electroencephalography* Euphoria / drug effects Heroin / adverse effects Heroin Dependence / rehabilitation* Humans Methadone / therapeutic use* Rest Theta Rhythm |
| Chemical | |
Reg. No./Substance:
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561-27-3/Heroin; 76-99-3/Methadone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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