| EEG-fMRI as an useful tool to detect epileptic foci associated with secondary bilateral synchrony. | |
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MedLine Citation:
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PMID: 20933440 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Tailoring the epileptic cortex is the key issue in the pre-surgical work-up of patients with pharmacoresistant focal epilepsy. Not always, however, the conventional MRI and the scalp EEG are able to provide the information needed to address this issue since the imaging may be normal (criptogenetic epilepsy) and the EEG, even ictal, poorly localizing. PATIENT AND METHODS: We present a case of focal criptogenetic epilepsy with speech arrest seizures and bilateral synchronous spike and wave scalp EEG pattern (secondary bilateral synchrony). The patient underwent an EEG-fMRI continuous co-registration. RESULTS: The EEG-fMRI showed a clear cut activation of a BOLD signal during the epileptic discharge over the left Supplementary Motor Area (SMA) and, on lesser degree, over the homolateral motor strip. DISCUSSION: Knowledge and expertise about this technique has greatly increased over the last few years making it an useful tool for localizing purposes specially in patients with ambiguous scalp EEG and normal MRI just like the one we presented. |
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Authors:
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Paolo Borelli; Mirko Avesani; Emanuela Formaggio; Silvia Francesca Storti; Tiziano Zanoni; Giuseppe Moretto; Antonio Fiaschi; Roberto Cerini; Paolo Manganotti |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-10-08 |
Journal Detail:
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Title: Seizure : the journal of the British Epilepsy Association Volume: 19 ISSN: 1532-2688 ISO Abbreviation: Seizure Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-18 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306979 Medline TA: Seizure Country: England |
Other Details:
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Languages: eng Pagination: 605-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, P.le LA Scuro, 37134 Verona, Italy. paoloborelli@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / pathology, physiopathology Cortical Synchronization / physiology Electroencephalography* Epilepsies, Partial / diagnosis*, pathology, physiopathology Female Humans Magnetic Resonance Imaging* Monitoring, Physiologic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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