Document Detail

EEG burst-suppression pattern correlates with the instantaneous heart rate under isoflurane anaesthesia.
MedLine Citation:
PMID:  2275329     Owner:  NLM     Status:  MEDLINE    
The correlation between electroencephalogram (EEG) and instantaneous heart rate was studied in deep isoflurane anaesthesia when the EEG showed a burst-suppression pattern in 15 patients aged 19-39 years. At the onset of EEG burst, the heart rate started to accelerate, and at the onset of suppression it started to decelerate. These changes in heart rate are similar to those we have previously described with enflurane, despite several differences in the effects of these two anaesthetics on EEG and on the cardiovascular system. We hypothesise that the heart-rate changes are due to central inhibition mediated by the vagus nerve during EEG suppression.
A Yli-Hankala; V Jäntti
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  34     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1991-02-22     Completed Date:  1991-02-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  665-8     Citation Subset:  IM    
Tampere University of Technology, Finland.
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MeSH Terms
Anesthesia, Inhalation*
Electroencephalography / drug effects*
Enflurane / pharmacology
Heart Rate / drug effects*,  physiology
Isoflurane / administration & dosage,  pharmacology*
Reg. No./Substance:
13838-16-9/Enflurane; 26675-46-7/Isoflurane

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