Document Detail

EEG, brain maturation, and the development of retinopathy of prematurity.
MedLine Citation:
PMID:  22630132     Owner:  NLM     Status:  Publisher    
Abstract Objectives: The factors that influence the CNS development can affect either the retina or the brain cortex. Immaturity of the brain cortex reflects immaturity of the retina and vice versa. The immature retina is more vulnerable than the mature retina, and is therefore more likely to develop retinopathy of prematurity (ROP). The aim of this study was to compare electroencephalographic brain maturity with ROP severity. Methods: Twenty-one prematurely born infants were divided into two groups according to the severity of ROP. The first group included 12 infants with ROP stage 3 or more, and the second group included 9 infants with ROP stage 2 or less. We have proposed an index of CNS maturity (M) as a percentage of interburst interval elongation compared with the norm using vEEG. Results: The median M value was 1.07 (range, 0.43 to 4.44) for infants with severe ROP and -0.1 (range, -1.0 to 1.45) for infants with mild or no ROP (p = 0.000948). Conclusions: The study revealed that CNS maturation delay expressed as M value was higher among infants with severe ROP than among infants with mild or no ROP. EEG examination in prematurely born infants may prove to be a useful tool for predicting ROP development.
Wojciech Podraza; Hanna Podraza; Karolina Jezierska; Joanna Szwed; Hanna Domek; Agnieszka Kordek; Monika Modrzejewska; Jacek Rudnicki
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-28
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Medical Physics, Pomeranian Medical University, Szczecin, Poland.
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