Document Detail

ECG-gated multi-detector row spiral CT in the assessment of myocardial infarction: correlation with non-invasive angiographic findings.
MedLine Citation:
PMID:  16402255     Owner:  NLM     Status:  MEDLINE    
Our objective was to retrospectively evaluate the ability of multidetector-row computed tomography (MDCT) to detect previous myocardial infarctions (MIs) and to correlate necrosis with the status of coronary arteries supplying the infarcted territory. After having clinically evaluated 187 patients referred for ECG-gated MDCT of the coronary arteries, 30 previous MIs were identified in 29 patients (9 recent and 21 chronic). MDCT data were evaluated qualitatively and quantitatively by measuring attenuation values and wall thickness within the infarcted region and normal adjacent myocardium. Each MI was also assigned to the distribution territory of a coronary vessel, and morphological data were combined with MDCT angiographic findings. MDCT was able to detect 25/30 MIs showing an overall sensitivity and specificity of 83 and 91%, respectively. Quantitative analysis revealed a statistically significant difference in attenuation values between normal and infarcted regions (38.9+/-14 HU vs. 104.0+/-16 HU). Regional wall thinning was observed in chronic MIs (4.1+/-2 mm vs. 10.5+/-3.8 mm), and not in patients with recent event (7.9+/-1.6 mm vs 9.1+/-4 mm). In 22/25 cases, MDCT angiographic findings showed the presence of suspicious critical lumen narrowing (n=3), previous coronary stenting (n=14) and surgical revascularization (n=5) in the infarct-related coronary. During a single examination, MDCT might provide comprehensive imaging of MI offering a combined morphological and angiographic assessment.
Marco Francone; Iacopo Carbone; Massimiliano Danti; Katia Lanciotti; Mario Cavacece; Francesca Mirabelli; Carlo Gaudio; Carlo Catalano; Roberto Passariello
Related Documents :
23355585 - Acute myocardial infarction and heart block: a challenge to emergency physicians.
3216165 - Effects of pulmonary emphysema on qrs infarct size score.
16168815 - Dual-isotope myocardial spect in patients with redefined myocardial infarction.
19340355 - Acetylcholine-regulated k+ current remodelling in the atrium after myocardial infarctio...
2193495 - Analysis of possible triggers of acute myocardial infarction (the milis study).
20719735 - Accessory mitral valve causing left ventricular outflow tract obstruction.
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2005-06-14
Journal Detail:
Title:  European radiology     Volume:  16     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-10     Completed Date:  2006-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  15-24     Citation Subset:  IM    
Department of Radiological Sciences, University of Rome La Sapienza, V.le Regina Elena 324, 00161, Rome, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Coronary Angiography / methods*
Electrocardiography / methods*
Middle Aged
Myocardial Infarction / complications,  diagnosis*
Necrosis / etiology
Observer Variation
Retrospective Studies
Sensitivity and Specificity
Tomography, Spiral Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Can 16-detector multislice CT exclude skeletal lesions during tumour staging? Implications for the c...
Next Document:  13C imaging-a new diagnostic platform.