Document Detail


EC-IC bypass function in Moyamoya disease and non-Moyamoya ischemic stroke evaluated by intraoperative indocyanine green fluorescence angiography.
MedLine Citation:
PMID:  20204839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Indocyanine green (ICG) emits near-infrared fluorescence when it is excited by near-infrared light. The near infrared fluorescence of ICG was applied to the imaging of cerebral vessels during neurosurgical operations such as clipping of aneurysms. In this study, ICG angiography was applied to extracranial-intracranial (EC-IC) bypass surgery to evaluate the hemodynamic changes induced by bypass in moyamoya disease (MD) and non-moyamoya ischemic diseases (non-MD). These patients underwent superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis. We compared the cortical areas where the bypass supplied blood flow between MD and non-MD. ICG angiography clearly demonstrated the bypass blood flow from the anastomosed STA to the cortical vessels including arteries, capillaries, and veins in both MD and non-MD. Interestingly, the anastomosed STA supplied blood flow to a larger cortical area in MD than non-MD. The bypass supplied greater extent of blood flow to the ischemic brain in MD than in non-MD. This difference might be caused by the fact that the perfusion pressure was lower in MD than in non-MD.
Authors:
Takayuki Awano; Kaoru Sakatani; Noriaki Yokose; Tatsuya Hoshino; Norio Fujiwara; Shin Nakamura; Yoshihiro Murata; Tsuneo Kano; Yoichi Katayama; Takahiro Shikayama; Mitsuharu Miwa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  662     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-05     Completed Date:  2010-03-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  519-24     Citation Subset:  IM    
Affiliation:
Division of Neurosurgery, Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan. awntkyk1556@yahoo.co.jp
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MeSH Terms
Descriptor/Qualifier:
Anastomosis, Surgical
Brain Ischemia / complications,  physiopathology*,  radiography
Cerebral Revascularization / methods*
Fluorescein Angiography / methods*
Humans
Indocyanine Green / diagnostic use*
Intraoperative Care*
Middle Aged
Middle Cerebral Artery / surgery
Moyamoya Disease / complications,  physiopathology*,  radiography
Stroke / etiology,  physiopathology*,  radiography
Temporal Arteries / surgery
Young Adult
Chemical
Reg. No./Substance:
3599-32-4/Indocyanine Green

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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