| EBV-associated haemophagocytic syndrome in a patient with Behçet's disease. | |
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MedLine Citation:
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PMID: 16195167 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present a case of Epstein-Barr virus (EBV)-associated haemophagocytic syndrome in a patient with Behçet's disease. A 43-year-old man, who had been receiving treatment under the diagnosis of Behçet's disease for recurrent oral ulcers, genital ulcer, ileal ulcer, and arthritis, had been admitted for fever, headache, and nausea developed 3 days ago. Laboratory data showed pancytopaenia, an increase in liver enzymes, lactate dehydrogenase (LDH) and ferritin. Haemophagocytic syndrome was diagnosed from histiocytosis and haemophagocytosis by macrophages, shown in the bone marrow aspiration and biopsy, and in situ hybridization for EBV showed a positive finding. The patient recovered rapidly after steroid therapy. This is the first report of EBV-associated haemophagocytic syndrome developed in a patient with Behçet's disease. |
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Authors:
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S-H Lee; S-D Kim; S-H Kim; H-R Kim; E-J Oh; C-H Yoon; S-H Lee; H-Y Kim; S-H Park |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Scandinavian journal of rheumatology Volume: 34 ISSN: 0300-9742 ISO Abbreviation: Scand. J. Rheumatol. Publication Date: 2005 Jul-Aug |
Date Detail:
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Created Date: 2005-09-30 Completed Date: 2005-11-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0321213 Medline TA: Scand J Rheumatol Country: Norway |
Other Details:
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Languages: eng Pagination: 320-3 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Division of Rheumatology, Kangnam St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents / therapeutic use Behcet Syndrome / complications*, diagnosis, drug therapy Bone Marrow Cells / cytology Cyclosporine / therapeutic use Drug Therapy, Combination Epstein-Barr Virus Infections / complications*, diagnosis, drug therapy Follow-Up Studies Herpesvirus 4, Human / isolation & purification* Histiocytosis, Non-Langerhans-Cell / complications*, diagnosis, drug therapy Humans Male Prednisolone / therapeutic use Risk Assessment Severity of Illness Index Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 50-24-8/Prednisolone; 59865-13-3/Cyclosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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