Document Detail


E-rosettes in aging: meta-analysis of the literature.
MedLine Citation:
PMID:  3046535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this meta-analysis of the literature, it is affirmed that aging is associated with a small but significant decline in peripheral E-rosette-forming cells while high affinity E-rosettes (active or early rosettes) increase. The author speculates that this differential age effect may reflect the abnormal capping behaviour of E-rosettes or a change in the cell surface charge properties. A type II error is a common trait of the reviewed studies and could well explain the great number of reports concluding that E-rosette-forming cells are unaltered in the elderly.
Authors:
D Brohée
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of gerontology and geriatrics     Volume:  7     ISSN:  0167-4943     ISO Abbreviation:  Arch Gerontol Geriatr     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-09-29     Completed Date:  1988-09-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8214379     Medline TA:  Arch Gerontol Geriatr     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  179-87     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, C.H.U. André Vésale, Montigny-le-Tilleul, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aging / immunology*
Humans
Lymphocytes / classification,  immunology*
Research Design
Rosette Formation*

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