| E-rosette formation, total T-cells, and lymphocyte transformation in infants receiving intravenous safflower oil emulsion. | |
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MedLine Citation:
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PMID: 6418909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There has been much concern about impaired immune function in children receiving infused lipid emulsions. Immunologic studies were carried out on 15 infants maintained on parenteral nutrition with intravenous safflower oil emulsion as part of the infusate. Significant increases in percentage rosette formation, total circulating T-cells, and mitogenesis to phytohemagglutinin and pokeweed mitogen were demonstrated after only 1 wk of lipid infusion. Additional parenteral nutrition did not further increase any immunologic parameter. These results suggest that infused safflower oil emulsion does not adversely alter cellular immune function. |
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Authors:
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R A Helms; H G Herrod; G J Burckart; M L Christensen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: JPEN. Journal of parenteral and enteral nutrition Volume: 7 ISSN: 0148-6071 ISO Abbreviation: JPEN J Parenter Enteral Nutr Publication Date: 1983 Nov-Dec |
Date Detail:
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Created Date: 1984-02-14 Completed Date: 1984-02-14 Revised Date: 2007-02-21 |
Medline Journal Info:
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Nlm Unique ID: 7804134 Medline TA: JPEN J Parenter Enteral Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 541-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Fat Emulsions, Intravenous* Female Humans Immunity, Cellular* Infant Infant Care Infant, Newborn Leukocyte Count Lymphocyte Activation Male Parenteral Nutrition Rosette Formation Safflower Oil T-Lymphocytes / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Fat Emulsions, Intravenous; 8001-23-8/Safflower Oil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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