Document Detail


E-rosette formation, total T-cells, and lymphocyte transformation in infants receiving intravenous safflower oil emulsion.
MedLine Citation:
PMID:  6418909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There has been much concern about impaired immune function in children receiving infused lipid emulsions. Immunologic studies were carried out on 15 infants maintained on parenteral nutrition with intravenous safflower oil emulsion as part of the infusate. Significant increases in percentage rosette formation, total circulating T-cells, and mitogenesis to phytohemagglutinin and pokeweed mitogen were demonstrated after only 1 wk of lipid infusion. Additional parenteral nutrition did not further increase any immunologic parameter. These results suggest that infused safflower oil emulsion does not adversely alter cellular immune function.
Authors:
R A Helms; H G Herrod; G J Burckart; M L Christensen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JPEN. Journal of parenteral and enteral nutrition     Volume:  7     ISSN:  0148-6071     ISO Abbreviation:  JPEN J Parenter Enteral Nutr     Publication Date:    1983 Nov-Dec
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2007-02-21    
Medline Journal Info:
Nlm Unique ID:  7804134     Medline TA:  JPEN J Parenter Enteral Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  541-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Fat Emulsions, Intravenous*
Female
Humans
Immunity, Cellular*
Infant
Infant Care
Infant, Newborn
Leukocyte Count
Lymphocyte Activation
Male
Parenteral Nutrition
Rosette Formation
Safflower Oil
T-Lymphocytes / immunology*
Chemical
Reg. No./Substance:
0/Fat Emulsions, Intravenous; 8001-23-8/Safflower Oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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