Document Detail

Dystonic reaction following recommended use of a cold syrup.
MedLine Citation:
PMID:  7492048     Owner:  NLM     Status:  MEDLINE    
A healthy 3-year-old boy presented to our emergency department with sudden onset of abnormal movement. This patient had been treated for 2 days with conventional doses of an antihistamine/decongestant cold preparation for upper respiratory infection symptoms. The child was confused and restless, with posturing of limbs. Cranial nerve function was intact. Gastric lavage yielded an aspirate the same color as the cold syrup the child had ingested. A diagnosis of dystonic reaction was made, and the child was treated with benztropine, which effected resolution of his symptoms. This is the first reported case in the literature of dystonia induced by an antihistamine and treated with benztropine.
M M Joseph; W D King
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  26     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-01-04     Completed Date:  1996-01-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  749-51     Citation Subset:  AIM; IM    
Department of Pediatric Emergency Medicine, University of Florida Health Science Center, Jacksonville, USA.
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MeSH Terms
Benztropine / therapeutic use*
Child, Preschool
Diphenhydramine / adverse effects*
Drug Combinations
Dystonia / chemically induced*,  drug therapy
Histamine H1 Antagonists / adverse effects*
Nasal Decongestants / adverse effects
Phenylpropanolamine / adverse effects
Reg. No./Substance:
0/Drug Combinations; 0/Histamine H1 Antagonists; 0/Nasal Decongestants; 14838-15-4/Phenylpropanolamine; 58-73-1/Diphenhydramine; 86-13-5/Benztropine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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