Document Detail

Dysphagia as a manifestation of thyrotoxicosis: report of three cases and literature review.
MedLine Citation:
PMID:  15382800     Owner:  NLM     Status:  MEDLINE    
Myopathy is frequently associated with thyrotoxicosis. Skeletal muscles are predominantly involved in thyrotoxic myopathy, but dysphagia is extremely rare. We report three cases of thyrotoxicosis with dysphagia and review of the literature of the past 30 years. Most of these patients had antecedent muscle weakness before the onset of dysphagia although some suffered from a sudden onset of bulbar palsy. Either a myopathic or neuropathic pattern was found on electromyography. The incidence of oropharyngeal dysphagia was higher than that of esophageal motility dysfunction. Aspiration pneumonia occurred more accompanied by oropharyngeal dysphagia. The swallowing disorder could be resolved completely within 3 weeks after treatment for thyrotoxicosis. In light of these clinical experiences, early intensive treatment that includes antithyroid agent, beta-blocker, and Lugol solution may be necessary.
Wei-Yih Chiu; Chih-Chao Yang; I-Chueh Huang; Tien-Shang Huang
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Dysphagia     Volume:  19     ISSN:  0179-051X     ISO Abbreviation:  Dysphagia     Publication Date:  2004  
Date Detail:
Created Date:  2004-09-22     Completed Date:  2004-12-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8610856     Medline TA:  Dysphagia     Country:  United States    
Other Details:
Languages:  eng     Pagination:  120-4     Citation Subset:  D; IM    
Department of Internal Medicine, College of Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
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MeSH Terms
Aged, 80 and over
Deglutition Disorders / etiology*,  physiopathology
Middle Aged
Muscular Diseases / etiology
Thyrotoxicosis / complications*

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