Document Detail


Dysmenorrhea induced by autologous transfusion.
MedLine Citation:
PMID:  7266947     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A circulating factor capable of inducing symptoms of dysmenorrhea has been demonstrated in 10 women by collecting plasma during periods of dysmenorrhea and infusing it during asymptomatic intervals. Typical symptoms of abdominal pain occurred in 8 of 12 women who received a plasma infusion that had been drawn at the time symptoms were present. Plasma drawn at the time of no symptoms, when given to 10 women, produced no abdominal pain (P less than .01). Combinations of pain and/or emotional irritability were found in 11 of 12 women after symptomatic units were infused and in only 2 of 10 women after asymptomatic units were infused (P less than .001). The uterus need not be involved, as 7 of 10 patients had a hysterectomy prior to the infusions. It is suggested that a circulating factor may activate prostaglandin synthesis, which in turn may stimulate the neuronal system, thus causing symptoms.
Authors:
J Irwin; E Morse; D Riddick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  58     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1981 Sep 
Date Detail:
Created Date:  1981-10-25     Completed Date:  1981-10-25     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  286-90     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Abdomen
Adult
Blood Transfusion, Autologous / adverse effects
Dysmenorrhea / etiology*
Female
Humans
Hysterectomy
Nervous System Physiological Phenomena
Pain / etiology
Prostaglandins / biosynthesis,  physiology
Chemical
Reg. No./Substance:
0/Prostaglandins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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