Document Detail


Dyslipidemia therapy update: the importance of full lipid profile assessment.
MedLine Citation:
PMID:  19649582     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lipid guidelines typically focus on total cholesterol +/- low-density lipoprotein cholesterol levels with less emphasis on high-density lipoprotein cholesterol (HDL-C) or triglyceride assessment, thus potentially underestimating cardiovascular (CV) risk and the need for lifestyle or treatment optimization. In this article, we highlight how reliance on isolated total cholesterol assessment may miss prognostically relevant lipid abnormalities; we describe from the European Systematic COronary Risk Evaluation (SCORE) data set how incorporation of HDL-C may improve estimation of CV risk; and, finally, we critically evaluate the evidence base surrounding triglycerides and CV risk.
Authors:
I B A Menown; G Murtagh; V Maher; M T Cooney; I M Graham; G Tomkin
Publication Detail:
Type:  Journal Article; Review     Date:  2009-07-27
Journal Detail:
Title:  Advances in therapy     Volume:  26     ISSN:  0741-238X     ISO Abbreviation:  Adv Ther     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-08-03     Completed Date:  2009-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8611864     Medline TA:  Adv Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  711-8     Citation Subset:  T    
Affiliation:
Craigavon Cardiac Centre, Craigavon BT63 5QQ, Northern Ireland, UK. ian.menown@southerntrust.hscni.net
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MeSH Terms
Descriptor/Qualifier:
Atherosclerosis / blood,  diagnosis
Cardiovascular Diseases / blood,  diagnosis*
Cholesterol / blood*
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Dyslipidemias / blood*,  diagnosis*,  therapy
Humans
Practice Guidelines as Topic
Risk Assessment
Triglycerides / blood*
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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