| Dyslipidemia, low left ventricular ejection fraction and high wall motion score index are predictors of progressive left ventricular dilatation after acute myocardial infarction. | |
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MedLine Citation:
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PMID: 21519510 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVES: Left ventricular (LV) remodeling is a heterogeneous process, involving both infarcted and non-infarcted zones, which affects wall thickness and chamber size, shape and function. SUBJECTS AND METHODS: A total of 758 consecutive patients (62.8±12.0 years, 539 males) with acute myocardial infarction (AMI), who were examined by echocardiography at admission and after 6 months. An increase in LV end-diastolic volume index >10% was defined as a progressive LV dilation. They were divided into two groups according to the extent of progressive LV dilatation during 6 months. Group I with progressive LV dilatation (n=154, 61.4±11.0 years, 110 males) vs. group II without LV dilatation (n=604, 64.1±12.0 years, 429 males). RESULTS: The age and gender were no significant differences between two groups. The levels of glucose, creatinine, maximal creatine kinase (CK), CK-MB, troponin T and I were significantly increased in group I than in group II (p<0.05). Low ejection fraction (EF) and high wall motion score index (WMSI) were more common in group I than in group II (p<0.05). The presence of dyslipidemia {odds ratio (OR); 1.559, confidence interval (CI); 1.035-2.347, p=0.03}, low EF less than 45% (OR; 3.328, CI 2.099-5.276, p<0.01) and high WMSI above 1.5 (OR; 3.328, CI 2.099-5.276, p<0.01) were sig-nificant independent predictors of progressive LV dilatation by multivariate analysis. CONCLUSION: Dyslipidemia, decreased systolic function and high WMSI were independent predictors of LV remodeling process in patients with AMI. |
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Authors:
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Hyun Ju Yoon; Myung Ho Jeong; Jang Ho Bae; Kye Hun Kim; Youngkeun Ahn; Jeong Gwan Cho; Jong Chun Park; Jung Chaee Kang |
Publication Detail:
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Type: Journal Article Date: 2011-03-31 |
Journal Detail:
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Title: Korean circulation journal Volume: 41 ISSN: 1738-5555 ISO Abbreviation: Korean Circ J Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-04-26 Completed Date: 2011-07-14 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 101247141 Medline TA: Korean Circ J Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 124-9 Citation Subset: - |
Affiliation:
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Heart Center of Chonnam National University Hospital, Gwangju, Korea. |
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