Document Detail


Dyslipidemia in Asian Indians: determinants and significance.
MedLine Citation:
PMID:  15656049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Data suggest that lipid fractions other than total cholesterol, i.e. serum triglycerides (TG) and high-density lipoprotein (HDL) cholesterol are important for the pathogenesis of atherosclerosis. A combination of hypertriglyceridemia, low levels of HDL-cholesterol and high levels of small dense low-density lipoprotein, termed as "atherogenic dyslipidemia', is particularly seen in Asian Indians. Although precise reason for such dyslipidemia is unknown, genetic predisposition and characteristic body composition (excess truncal subcutaneous fat and intraabdominal fat) may be important contributors. A common interface between such body composition and dyslipidemia in Asian Indians is high tendency to develop insulin resistance, more than the other ethnic groups. The general guidelines for the management of dyslipidemia in Asian Indians should be according to National Cholesterol Education Program, Adult Treatment Panel III. However, optimal management requires consideration of ethnic-specific dietary, lifestyle and management factors to formulate individual treatment guidelines.
Authors:
A Misra; Kalpana Luthra; N K Vikram
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  52     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2005-01-19     Completed Date:  2005-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM    
Affiliation:
Dept. of Medicine, All India Institute of Medical Sciences, New Delhi-110 029, India.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Aged
Asian Continental Ancestry Group / statistics & numerical data*
Cholesterol, HDL / analysis
Cholesterol, LDL / analysis
Female
Humans
Hyperlipidemias / diagnosis*,  ethnology*
Incidence
India / epidemiology
Insulin Resistance / ethnology*
Male
Middle Aged
Risk Assessment
Severity of Illness Index
Sex Distribution
Survival Rate
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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