| Dyslipidemia and adherence to the Mediterranean diet in Croatian HIV-infected patients during the first year of highly active antiretroviral therapy. | |
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MedLine Citation:
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PMID: 19662759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated the association of adherence to the Mediterranean diet and other risk factors for dyslipidemia in HIV-infected Croatian patients during the first year of highly active antiretroviral therapy (HAART). Adherence to the Mediterranean diet was determined by a 150-item questionnaire; a 0 to 9-point diet scale was created that stratified respondents as having low adherence (<4 points) and moderate to high adherence (> or = 4 points). We interviewed 117 participants between May 2004 and June 2005 and abstracted their serum lipid measurements taken during the first year of HAART The values of total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides increased most prominently in the first 3 to 6 months after initiation of HAART (average increase at 3 months: 25% for total cholesterol, 22% for LDL-cholesterol, 18% for HDL-cholesterol and 43% for triglycerides). A Mediterranean diet and physical activity had no effect on serum lipids. The mean total cholesterol was higher in participants receiving a combination of a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor compared to participants receiving a combination of nucleoside analogs with a non-nucleoside analog or a combination of nucleoside analogs and a protease inhibitor Among individual drug treatments, indinavir/ritonavir had the most unfavorable lipid profile. We conclude that adherence to a Mediterranean diet does not influence serum lipid profiles during the first year of HAART. |
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Authors:
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Drago Turcinov; Christine Stanley; Jesse A Canchola; George W Rutherford; Thomas E Novotny; Josip Begovac |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Collegium antropologicum Volume: 33 ISSN: 0350-6134 ISO Abbreviation: Coll Antropol Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-08-10 Completed Date: 2009-09-14 Revised Date: 2011-05-03 |
Medline Journal Info:
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Nlm Unique ID: 8003354 Medline TA: Coll Antropol Country: Croatia |
Other Details:
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Languages: eng Pagination: 423-30 Citation Subset: IM |
Affiliation:
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University Hospital for Infectious Diseases, Zagreb, Croatia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antiretroviral Therapy, Highly Active* Croatia / epidemiology Diet, Mediterranean* Dyslipidemias / diet therapy*, epidemiology* Female HIV Infections / drug therapy*, epidemiology* Humans Male Middle Aged Questionnaires Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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R25 MH064712-05/MH/NIMH NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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