| Dysfunctional niches as a root of hematopoietic malignancy. | |
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MedLine Citation:
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PMID: 20452309 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Whether the bone marrow microenvironment can contribute to development of blood borne cancers is controversial. In a recent issue of Nature, Raaijmakers et al. (2010) show that deletion of Dicer1 specifically in osteoprogenitors not only impaired their differentiation but also resulted in disrupted blood formation and secondary leukemia. |
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Authors:
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Yusuke Shiozawa; Russell S Taichman |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Cell stem cell Volume: 6 ISSN: 1875-9777 ISO Abbreviation: Cell Stem Cell Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-10 Completed Date: 2010-09-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101311472 Medline TA: Cell Stem Cell Country: United States |
Other Details:
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Languages: eng Pagination: 399-400 Citation Subset: - |
Affiliation:
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Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA. |
Export Citation:
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Descriptor/Qualifier:
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| Comments/Corrections | |
Comment On:
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Nature. 2010 Apr 8;464(7290):852-7
[PMID:
20305640
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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