Document Detail


Dysfunctional autogenous hemodialysis fistulas: outcomes after angioplasty--are there clinical predictors of patency?
MedLine Citation:
PMID:  15286321     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine the primary and secondary patency rates for fistulas treated with angioplasty, as well as clinical predictors of fistula patency after angioplasty. MATERIALS AND METHODS: The authors reviewed their institutional experience with autogenous fistulas from June 1997 to June 2002. A total of 104 men and 36 women were treated. Mean age +/- standard deviation of patient cohort was 62.4 years +/- 15.6. Patient age and sex, age of fistula at initial intervention, presence of diabetes, side and location of fistula, location of stenosis, and number of venous stenoses dilated were examined. Patency after angioplasty was estimated by using the Kaplan-Meier method, and predictors of patency were examined by using a Cox proportional hazards model. RESULTS: One hundred fifty-one dysfunctional fistulas (94 radiocephalic and 57 brachiocephalic) were treated with angioplasty initially. Clinical success rate was 98.0% (297 of 303 interventions). At 3, 6, and 12 months, respectively, primary patency rates +/- standard errors of the estimate were 73% +/- 6, 51% +/- 7, and 39% +/- 7 for brachiocephalic fistulas and 85% +/- 4, 75% +/- 5, and 62% +/- 5 for radiocephalic fistulas; secondary patency rates were 96% +/- 2.4, 89% +/- 4, and 85% +/- 5 for brachiocephalic fistulas and 91% +/- 3, 88% +/- 3, and 86% +/- 4 for radiocephalic fistulas. For all time points, there was a significant difference in primary (P =.004) but not secondary (P =.45) patency between radiocephalic and brachiocephalic fistulas. Stenosis was most prevalent within 3 cm of the arteriovenous anastomosis in 74 (64%) of the 116 dysfunctional radiocephalic fistulas and at the cephalic arch in 22 (30%) of the 74 dysfunctional brachiocephalic fistulas. The clinical variables examined did not influence outcome. Complications occurred in seven (2.3%) of 303 interventions. CONCLUSION: Patency after angioplasty in dysfunctional autogenous hemodialysis fistulas exceeds that observed in hemodialysis grafts. None of the clinical or anatomic variables examined affected patency outcome.
Authors:
Dheeraj K Rajan; Sarah Bunston; Sanjay Misra; Ruxandra Pinto; Charmaine E Lok
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  232     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-02     Completed Date:  2004-09-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  508-15     Citation Subset:  AIM; IM    
Copyright Information:
Copyright RSNA, 2004
Affiliation:
Department of Medical Imaging, Division of Vascular and Interventional Radiology, Toronto General Hospital, University Health Network, University of Toronto, 585 University Ave, NCSB 1C-553, Toronto, ON, Canada M5G 2N2. dheeraj.rajan@uhn.on.ca
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MeSH Terms
Descriptor/Qualifier:
Aged
Angioplasty, Balloon*
Arteriovenous Shunt, Surgical
Cohort Studies
Female
Graft Occlusion, Vascular / therapy*
Humans
Male
Middle Aged
Outcome Assessment (Health Care) / statistics & numerical data
Proportional Hazards Models
Renal Dialysis*
Retrospective Studies
Risk Factors
Treatment Outcome
Vascular Patency / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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