| Dynamics of ventilation, circulation, and gas exchange to incremental and decremental ramp exercise. | |
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MedLine Citation:
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PMID: 1629079 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Transient responses of minute volume (VE), O2 uptake (VO2), CO2 output (VCO2), heart rate (HR), and cardiac output (Q) to a step change and ramp changes with slopes ranging from 33.3 to 14.3 W/min were studied in five healthy human subjects over the load range from 25 to 125 W. The ramp responses were fitted to a first-order model with a pure time delay (td) and a time constant (TC), while most of the step responses fitted better to a second-order model, consisting of a fast and a slow component. No significant asymmetry was observed between the on- and off-responses to step forcing. The mean response time (MRT = td+TC) of the incremental ramp response was prolonged, whereas the MRT of the decremental ramp response was shortened or unchanged, with decreasing ramp slope. The asymmetry was commonly observed in respiratory and gas exchange variables and, to a lesser extent, also in circulatory variables. Neural and humoral factors that might be responsible for this phenomenon are discussed. |
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Authors:
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Y Miyamoto; Y Niizeki |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 72 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1992 Jun |
Date Detail:
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Created Date: 1992-08-19 Completed Date: 1992-08-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2244-54 Citation Subset: IM; S |
Affiliation:
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Department of Electrical and Information Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Circulation / physiology* Carbon Dioxide Cardiac Output / physiology Exercise / physiology* Heart Rate / physiology Humans Kinetics Male Oxygen Consumption / physiology Pulmonary Gas Exchange / physiology Respiration / physiology* |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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