Document Detail

Dynamics of reepithelialisation and penetration rate of a bee propolis formulation during cutaneous wounds healing.
MedLine Citation:
PMID:  19200487     Owner:  NLM     Status:  MEDLINE    
The aim of this work is to investigate the dynamics of reepithelialisation and the penetration rate of a propolis ointment formulation during cutaneous wounds healing. The experiments were performed as a function of the treatment time in a well controlled group of rats. We observed that the propolis ointment influenced the healing process stimulating keratinocytes cell proliferation as compared to the control group. It was shown that the propagation of the bee propolis was dependent on the wound healing stages. In addition, the photoacoustic spectroscopy showed that the applied substances reached the deep wound region, highlighting once again the particular characteristic of this technique to evaluate the penetration rate of substances through the skin.
E Sehn; L Hernandes; S L Franco; C C M Gonçalves; M L Baesso
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-17
Journal Detail:
Title:  Analytica chimica acta     Volume:  635     ISSN:  1873-4324     ISO Abbreviation:  Anal. Chim. Acta     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-03-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370534     Medline TA:  Anal Chim Acta     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  115-20     Citation Subset:  IM    
Departamento de Física, Universidade Estadual de Maringá, Avenida Colombo 5790, Maringá, Paraná, 87020-900, Brazil.
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MeSH Terms
Epithelial Cells / cytology*
Rats, Wistar
Skin / injuries*
Wound Healing*
Reg. No./Substance:

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